Background: Digital devices such as computers, laptops, television (TV) and mobile phones were originally designed to support human beings' daily activities; however, they may produce several limitations as well as benefits. The main concern of the study was how the utilization of digital devices like laptops, computers and TVs affect the mental health of Nepal?s university students and what are the self-care practices utilized to manage problems? Method: 326 MPhil scholars of Nepal Open University (NOU) participated in this cross-sectional study. Digital devices pattern of use (i.e., TV, laptop and computer), mental health problems, and self-care practices among university students were assessed through a semi-structured questionnaire. Chi-square test and binary logistic regression were major statistical techniques used in the research. Results: The study?s researchers found the following mental health problems: depression (21.5%), loneliness (39.9%), anxiety (30.7%), and a loss of the sense of control (47.5%). Significant associations were found between sitting position with loneliness, age and anxiety and the daily use of computer with sense of control, loneliness, and anxiety. Additionally, computer use two to three times a week, laptop use in the evening and sitting on a chair or stool when using digital devices, stood as the main predictors respectively of the sense of control, loneliness, and depression. Few participants with mental health problems used medicine and meditation for self-care. Conclusion: The use of digital devices was associated with mental health problems. Patterns of using computers and the preferred time to use laptops were major contributing factors for one?s sense of control and loneliness, respectively. Therefore, an awareness programme concerning the use of digital devices and their effects on mental health should be communicated among university students.  Kulcsszavak: internet addiction, pathological internet use, mental health, digital devices, pattern of self-care, Nepal