Polycationic polymers have several applications for humans. Industrial, agricultural, and medical applications are all worthy of attention. Polycationic polymers have been around since the 1700s. To grasp this, major figures like Antoine Lavoisier, Jöns Jakob Berzelius, Wöhler, and Liebig must be mentioned. Organic molecules' chemical composition was better known by the 1820s and 1840s. Wöhler created the first organic chemical, urea, from inorganic ingredients, thereby killing the hypothesis of life. The "age of polymers" began in the mid-twentieth century, with the exact knowledge of the structure of biopolymers such as DNA, RNA, proteins, and cellulose. It is crucial to specify certain basic characteristics for the medical application of polymeric space nets, such as biocompatibility and biodegradability. To summarize, it has taken more than 300 years since modern chemistry's inception to address the medicinal uses of antimicrobial polymers.  Kulcsszavak: kémia történet, biopolimerek, antimikróbás szerek