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A cikk állandó MOB linkje:
http://mob.gyemszi.hu/detailsperm.jsp?PERMID=165604
MOB:2024/4
Szerzők:Peras, Mislav; Kulis, Tomislav; Marekovic, Ivana
Tárgyszavak:MÁGNESES REZONANCIA KÉPALKOTÁS; VÉR; SEPSIS
Folyóirat:Acta Microbiologica et Immunologica Hungarica - 2024. 71. évf. 4. sz.
[https://akjournals.com/view/journals/030/030-overview.xml]


  T2Bacteria panel used simultaneously with blood cultures helps to determine the etiology of bloodstream infections / Mislav Peras, Tomislav Kulis, Ivana Marekovic
  Bibliogr.: p. 284. - Abstr. eng. - DOI: https://doi.org/10.1556/030.2024.02417
  In: Acta Microbiologica et Immunologica Hungarica. - ISSN 1217-8950, eISSN 1588-2640 . - 2024. 71. évf. 4. sz., p. 280-284. : ill.


Bloodstream infections (BSI) result in significant morbidity and mortality rates, and delayed administration of appropriate antimicrobial treatment is a major predictor of poor outcomes. T2 magnetic resonance (T2MR(R)) (T2 Biosystems(R), Lexington, MA, USA) is an innovative technology that can rapidly identify pathogens from a sample of whole blood in a remarkably short time frame of 3-5 h.We are evaluating if the T2Bacteria Panel (T2BP) contributes to the etiological diagnosis of bloodstream infections when combined with standard blood cultures (BC). The study was performed between December 2018 and March 2019, and a total of 28 patients with suspected BSI were included. The most notable finding of our study was that the addition of T2BP to BC in a diagnostic workflow led to a statistically significant higher rate of T2BP-targeted bacteria identification in patients with suspected BSI (46.4% versus 7.1%, P 5 0.001) when compared to BC alone. Considering the measures of diagnostic accuracy, T2BP showed 100.00% sensitivity, 88.24% specificity, 100% negative predictive value (NPV), and 84.62% positive predictive value (PPV). Our findings give valuable insights for microbiologists and clinicians into this molecular method and its advantages in routine diagnostics of BSI.  Kulcsszavak: T2 magnetic resonance, blood culture, bloodstream infection, rapid diagnostics, bacteria identification